Kerning/Font off in Preview Mode

Hey all,

I'm running into a problem this morning that I have never seen before, and can't find anything here that seems to explain it. While working on the slides, everything appears to be fine, as below:

However, when I preview, the kerning goes CRAZY.

Any ideas? The fonts in general seem to be a off this morning- in slide view, the font is set to Myriad Pro, but the preview doesn't show as the same. Numerous people in my department are having the same issue. Any ideas on what we can do to fix this?

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