Searching for Mac Drawing Programs

Starting my new job and I was given an 08 Axiotron Notepad that I may use to create my own personal drawings which will work perfectly for now. It's running a Mac OS X version 10.5.6 and it has Sketchbook Express Installed. Anyway I'm looking for suggestions of programs that I may be use to create my own drawings specifically for the Mac. Also I'm also open to any program that I could install on the Axiotron that may help with e-learning development. I.e. movie editors, vector programs, presentation software or anything that is used specifically for the Mac.

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