Yep, it was actually the comparison matrix that led me to believe there would be issues. We have separate files for audio and screencast recorded video. I recorded the screencast video using Articulate's recording tool.
This is the text that led me to conclude it wouldn't work. Please advise if you think otherwise.
Mobile Safari can play only one audio or video file at a time. If you plan to deploy HTML5 content to be viewed on an iPad, take this mobile Safari limitation into consideration when designing your course.
This could also affect your screen recordings if they include audio. Mobile Safari cannot play both the video and the audio simultaneously.