Hi Rod! In your case, it sounds like best approach would be to do multiple choice rather than a Multiple select, and then make E the only correct answer. However, in general, I think that kind of question is confusing and tricky for the learner (including all the options as A, B, and C, and then also including an "A, B & C" option as option D or E) and should be avoided altogether. The reason I recommend against using "all of the above" and "none of the above" has nothing to do with the Storyline software, it only has to do with instructional design best practices. Usually those choices (all of the above and none of the above) are used too much and as a filler, instead of thinking of meaningful choices. Also, they can lead to confusion as I mentioned previously. That's why I Recommend against using them, and nothing to do with Articulate software. Hope this clarifies!