Hyperlinks have stopped working.

I was having pretty much the same issue with my course. The "mail to" link just stopped working on the last slide. The trigger still says, "when user clicks (email address), send email to (email address)." When this is live, it can be selected by keyboard and will open an email when triggered. However, when the user uses a mouse, it doesn't work (it highlights, but does not respond by opening an email).

I ended up trying Marc Cuypers' suggested Javascript code as a second trigger on the whole text box, and now you can click the email address with the mouse and it also works (so both keyboard and mouse get the response of opening an email).