There is definitely a bug with Markers in 360. I have the latest update installed. To replicate the issue, you can start a fresh project. Add two markers to the slide. Add whatever titles/body text you want. Apply a trigger to each to set the state to "disabled" when the marker is clicked. You will be able to click the first marker and it will function as expected, but the second marker will not work at all.
I'm afraid it's not an answer that can help Matt or anyone else, but hopefully Leslie and the engineers can fix this quickly.
Here is the simple project I sent to support as an example: https://360.articulate.com/review/content/f0452ca1-8588-4684-8e71-ed93e47a8e74/review