Storyline 360 x64 will not launch

I feel your pain. I have been there. Try one of the following:

1.Completely Close the Articulate 360 Desktop App:

Right-click the Articulate icon in your system tray (near the clock) and select "Quit" to ensure it's not running in the background.

2.Run Storyline 360 as Administrator:

Right-click the Storyline 360 shortcut and choose "Run as administrator". This can help bypass permission-related issues.

3.Check for Windows Updates:

Make sure your system is up to date by running Windows Update. Missing updates can sometimes cause compatibility issues.

4.Clear Temporary Files:

Navigate to C:\Users\[YourUsername]\AppData\Roaming\Articulate\Storyline and delete any .tmp files. Accumulated temporary files can interfere with the application's startup.

5.Check for Problematic Fonts:

Strange fonts, like Noto Sans and MS Mincho, have been known to cause issues. If you're using these fonts, you might want to replace them with standard fonts like Arial to see if that resolves the problem.

If none of these help I would say you need to give Support a shout to see if they can help out.  Make a note of what you have already done so they know.