Easiest way to align text boxes

Select all the objects under box 1, including your green box 1. 

I'm a stickler for lining things up.  I would place a small shape/square to the left of the green 1 box, and a duplicate on green box 4.

Then press CTRL on the keyboard and click on your 4 green boxes.  On the format ribbon at the top of the screen, click Arrange, Align, Align Middle, Distribute Horizontal.

Then delete the 2 shapes I added for "spacing".


Next, use your mouse (or use the CTRL button again) to click and drag an invisible area around  Box 1 and the blue boxes that are below it.

Click the Arrange, Align, Align Centre, Distribute Vertical

Select Box 2 and those below it - Arrange, Align, Align Centre,

Do the same for 3 and 4 columns

Then pick all the 200 boxes and click Arrange, Align, Align Top or bottom.

I arranged all the numbered boxes to be aligned with the left most blue boxes.  So I arranged 200, 400, 600 to the top,   and the 800 and 1000 boxes to the bottom.  (it just depended how they were floating/positioned.