Hello Man,
Thanks for reaching out!
You can achieve your design requirement by changing the state of your interactive object to 'Disabled' after it performs that action that its triggers are assigned to. For example, if you need a button to show a layer, and then afterwards change its state to 'Disabled', you'll want to setup your triggers to look something like this:
I've attached a sample project file so you can see a simple example of this in action.
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