Hi Philip,
I know a native Mac version has been a hot topic for some time and it's something we continue to discuss internally as well. Personally and professionally I use a Mac and run Windows within VMWare. It's super fast and I haven't run into any difficulty with the set up - I know a number of our forums users have shared similar things. You may want to take a look at a few forum discussions such as these for ideas and successes/challenges:
Also, Rise is completely web-based (released this week as a part of Articulate 360), so you can use Safari, Google Chrome, and Firefox browsers on your Mac to create responsive Rise courses.
See this article for a list of system requirements for Rise.