SCORM customization to remove slide?

Sam's comment aligns with my understanding of editing the source content itself. What you describe would be amazing but isn't currently something I've seen pulled off.

If the conditional changes you describe are predictable and simple enough, the next best thing would be some sort of .ini-like file. The implementation might not be a breeze for everyone, but the solution (as I've implemented with prior projects) would be to have the eLearning read a text file when it's launched, a text file that contains different settings and text.

One of my specific implementations was to adjust the number of scenarios available to learners in an eLearning hosted on a web server. Users would navigate to the course through an intranet URL, and when the course loaded, it would check a .js file that included a simple JSON object. One of the key-value pairs described the number of scenarios to allow the learner to choose from. The first ten scenarios were designed for learners taking customer-facing calls and the second ten scenarios were for learners taking client-facing calls. Some new hires needed to train on all 20 but some only needed to train on the first 10.

It didn't make sense to have two separate versions of the same course with one containing ten scenarios and one containing 20, but leadership didn't want to leave scenario selection up to the learners, and the course had no way of validating which ones a particular learner should've been taking, so we let one number variable in the .js file do it for us. Oh, a class is starting in a few weeks and they only need the first ten scenarios? Open up the course's .js file, change the 20 to a 10, and then save. The next time it ran, the course would check that file, and then use it to limit the learner on the scenario-selection screen.. The right-arrow would literally stop at 10, preventing the learner from accessing the subsequent scenarios. When it came time to open up the rest, edit the file back to a 20, and now the arrow can load the 11th scenario, and then the 12th...

If your alterations to the course are predictable enough, such as certain clients not needing certain slides, I can imagine a way to put that in a JS object, have it read at runtime, and then the course adapt to skip those slides. And if certain specific onscreen text is actually a variable that's loaded at runtime, that can be affected as well through that JSON.

This would require appreciable planning ahead, but it is doable so long as you're not wanting to change unpredictable things at the whim of every new client.