Accessibility for text boxes with states

I have a Storyline course that needs to be accessible.  There is an interactive screen where the learner clicks icons to reveal additional information.  That information is in a single text box.  Each click of an icon changes the state of the text box to reveal the appropriate information.  Since the text box can only appear in the focus order once, I'm assuming that this will be problematic for a screen reader.  Is that the case, or am I overlooking something?